HIB/SPOP inhibits Ci/Gli-mediated tumorigenesis by modulating the RNA Polymerase II components stabilities

Hedgehog (Hh) signaling mediated by transcription factor Ci/Gli plays a vital role in embryonic development and adult tissue homeostasis in invertebrates and vertebrates, whose dysregulation leads to many human disorders, including cancer. However, till now, cofactors of Ci/Gli which can affect tumo...

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Detalles Bibliográficos
Autores principales: Gao, Yuxue, Shan, Zhaoliang, Jian, Chunhua, Wang, Ying, Yao, Xia, Li, Shengnan, Ti, Xiuxiu, Zhao, Guochun, Liu, Chen, Zhang, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404538/
https://www.ncbi.nlm.nih.gov/pubmed/37554435
http://dx.doi.org/10.1016/j.isci.2023.107334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404538/
https://www.ncbi.nlm.nih.gov/pubmed/37554435
http://dx.doi.org/10.1016/j.isci.2023.107334

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