An unbiased seed-based RNAi selection screen identifies small RNAs that inhibit androgen signaling and prostate cancer cell growth

Blocking androgen receptor signaling is the mainstay of therapy for advanced prostate cancer (PCa). However, acquired resistance to single agents targeting this pathway results in the development of lethal castration-resistant PCa. Combination therapy approaches represent a promising strategy for th...

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Detalles Bibliográficos
Autores principales: Corbin, Joshua M., Georgescu, Constantin, Wang, Lin, Wren, Jonathan D., Bieniasz, Magdalena, Xu, Chao, Asch, Adam S., Ruiz Echevarría, Maria J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404560/
https://www.ncbi.nlm.nih.gov/pubmed/37554515
http://dx.doi.org/10.1016/j.omtn.2023.06.021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404560/
https://www.ncbi.nlm.nih.gov/pubmed/37554515
http://dx.doi.org/10.1016/j.omtn.2023.06.021

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