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Neuron-specific proteasome activation exerts cell non-autonomous protection against amyloid-beta (Aβ) proteotoxicity in Caenorhabditis elegans

Proteostasis reinforcement is a promising approach in the design of therapeutic interventions against proteinopathies, including Alzheimer's disease. Understanding how and which parts of the proteostasis network should be enhanced is crucial in developing efficient therapeutic strategies. The a...

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Detalles Bibliográficos
Autores principales: Panagiotidou, Eleni, Gioran, Anna, Bano, Daniele, Chondrogianni, Niki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404562/
https://www.ncbi.nlm.nih.gov/pubmed/37473700
http://dx.doi.org/10.1016/j.redox.2023.102817