Structural insights into the regulation of the human E2∼SUMO conjugate through analysis of its stable mimetic

Protein SUMOylation is a ubiquitylation-like post-translational modification (PTM) that is synthesized through an enzymatic cascade involving an E1 (SAE1:SAE2), an E2 (UBC9), and various E3 enzymes. In the final step of this process, the small ubiquitin-like modifier (SUMO) is transferred from the U...

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Detalles Bibliográficos
Autores principales: Goffinont, Stéphane, Coste, Franck, Prieu-Serandon, Pierre, Mance, Lucija, Gaudon, Virginie, Garnier, Norbert, Castaing, Bertrand, Suskiewicz, Marcin Józef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article Collection: Protein Structure and Folding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404613/
https://www.ncbi.nlm.nih.gov/pubmed/37247759
http://dx.doi.org/10.1016/j.jbc.2023.104870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404613/
https://www.ncbi.nlm.nih.gov/pubmed/37247759
http://dx.doi.org/10.1016/j.jbc.2023.104870

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