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Structural insights into the regulation of the human E2∼SUMO conjugate through analysis of its stable mimetic

Protein SUMOylation is a ubiquitylation-like post-translational modification (PTM) that is synthesized through an enzymatic cascade involving an E1 (SAE1:SAE2), an E2 (UBC9), and various E3 enzymes. In the final step of this process, the small ubiquitin-like modifier (SUMO) is transferred from the U...

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Detalles Bibliográficos
Autores principales:	Goffinont, Stéphane, Coste, Franck, Prieu-Serandon, Pierre, Mance, Lucija, Gaudon, Virginie, Garnier, Norbert, Castaing, Bertrand, Suskiewicz, Marcin Józef
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article Collection: Protein Structure and Folding
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404613/ https://www.ncbi.nlm.nih.gov/pubmed/37247759 http://dx.doi.org/10.1016/j.jbc.2023.104870

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