The Stathmin-2 membrane-targeting domain is required for axon protection and regulated degradation by DLK signaling

Axon integrity is essential for functional connectivity in the nervous system. The degeneration of stressed or damaged axons is a common and sometimes initiating event in neurodegenerative disorders. Stathmin-2 (Stmn2) is an axon maintenance factor that is depleted in amyotrophic lateral sclerosis,...

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Detalles Bibliográficos
Autores principales: Thornburg-Suresh, Emma J.C., Richardson, Jerianne E., Summers, Daniel W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404615/
https://www.ncbi.nlm.nih.gov/pubmed/37236359
http://dx.doi.org/10.1016/j.jbc.2023.104861

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404615/
https://www.ncbi.nlm.nih.gov/pubmed/37236359
http://dx.doi.org/10.1016/j.jbc.2023.104861

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