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The Stathmin-2 membrane-targeting domain is required for axon protection and regulated degradation by DLK signaling
Axon integrity is essential for functional connectivity in the nervous system. The degeneration of stressed or damaged axons is a common and sometimes initiating event in neurodegenerative disorders. Stathmin-2 (Stmn2) is an axon maintenance factor that is depleted in amyotrophic lateral sclerosis,...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404615/ https://www.ncbi.nlm.nih.gov/pubmed/37236359 http://dx.doi.org/10.1016/j.jbc.2023.104861 |