Mutational and biophysical analyses reveal a TFIIIC binding region in the TFIIF-related Rpc53 subunit of RNA polymerase III

The TFIIF-like Rpc53/Rpc37 heterodimer of RNA polymerase (pol) III is involved in various stages of transcription. The C-terminal region of Rpc53 dimerizes with Rpc37 to anchor on the lobe domain of the pol III cleft. However, structural and functional features of the Rpc53 N-terminal region had not...

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Detalles Bibliográficos
Autores principales: Shekhar, Arvind Chandra, Wu, Wen-Jin, Chen, Hung-Ta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article Collection: Gene Regulation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404625/
https://www.ncbi.nlm.nih.gov/pubmed/37230389
http://dx.doi.org/10.1016/j.jbc.2023.104859

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404625/
https://www.ncbi.nlm.nih.gov/pubmed/37230389
http://dx.doi.org/10.1016/j.jbc.2023.104859

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