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Mutational and biophysical analyses reveal a TFIIIC binding region in the TFIIF-related Rpc53 subunit of RNA polymerase III

The TFIIF-like Rpc53/Rpc37 heterodimer of RNA polymerase (pol) III is involved in various stages of transcription. The C-terminal region of Rpc53 dimerizes with Rpc37 to anchor on the lobe domain of the pol III cleft. However, structural and functional features of the Rpc53 N-terminal region had not...

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Detalles Bibliográficos
Autores principales:	Shekhar, Arvind Chandra, Wu, Wen-Jin, Chen, Hung-Ta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article Collection: Gene Regulation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404625/ https://www.ncbi.nlm.nih.gov/pubmed/37230389 http://dx.doi.org/10.1016/j.jbc.2023.104859

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