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Deciphering the biosynthesis of a novel lipid in Mycobacterium tuberculosis expands the known roles of the nitroreductase superfamily

Mycobacterium tuberculosis’s (Mtb) success as a pathogen is due in part to its sophisticated lipid metabolic programs, both catabolic and biosynthetic. Several of Mtb lipids have specific roles in pathogenesis, but the identity and roles of many are unknown. Here, we demonstrated that the tyz gene c...

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Detalles Bibliográficos
Autores principales: Grigg, Jason C., Copp, Janine N., Krekhno, Jessica M.C., Liu, Jie, Ibrahimova, Aygun, Eltis, Lindsay D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404671/
https://www.ncbi.nlm.nih.gov/pubmed/37328106
http://dx.doi.org/10.1016/j.jbc.2023.104924