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Deciphering the biosynthesis of a novel lipid in Mycobacterium tuberculosis expands the known roles of the nitroreductase superfamily
Mycobacterium tuberculosis’s (Mtb) success as a pathogen is due in part to its sophisticated lipid metabolic programs, both catabolic and biosynthetic. Several of Mtb lipids have specific roles in pathogenesis, but the identity and roles of many are unknown. Here, we demonstrated that the tyz gene c...
Autores principales: | Grigg, Jason C., Copp, Janine N., Krekhno, Jessica M.C., Liu, Jie, Ibrahimova, Aygun, Eltis, Lindsay D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404671/ https://www.ncbi.nlm.nih.gov/pubmed/37328106 http://dx.doi.org/10.1016/j.jbc.2023.104924 |
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