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Thymine DNA glycosylase mediates chromatin phase separation in a DNA methylation–dependent manner

Thymine DNA glycosylase (TDG) is an essential enzyme involved in numerous biological pathways, including DNA repair, DNA demethylation, and transcriptional activation. Despite these important functions, the mechanisms surrounding the actions and regulation of TDG are poorly understood. In this study...

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Detalles Bibliográficos
Autores principales: McGregor, Lauren A., Deckard, Charles E., Smolen, Justin A., Porter, Gabriela M., Sczepanski, Jonathan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404674/
https://www.ncbi.nlm.nih.gov/pubmed/37307918
http://dx.doi.org/10.1016/j.jbc.2023.104907