Identification of a novel mitochondria-localized LKB1 variant required for the regulation of the oxidative stress response

The tumor suppressor Liver Kinase B1 (LKB1) is a multifunctional serine/threonine protein kinase that regulates cell metabolism, polarity, and growth and is associated with Peutz-Jeghers Syndrome and cancer predisposition. The LKB1 gene comprises 10 exons and 9 introns. Three spliced LKB1 variants h...

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Detalles Bibliográficos
Autores principales: Tan, Ivan, Xu, Shengli, Huo, Jianxin, Huang, Yuhan, Lim, Hong-Hwa, Lam, Kong-Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404683/
https://www.ncbi.nlm.nih.gov/pubmed/37302555
http://dx.doi.org/10.1016/j.jbc.2023.104906

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404683/
https://www.ncbi.nlm.nih.gov/pubmed/37302555
http://dx.doi.org/10.1016/j.jbc.2023.104906

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