Protein engineering of a nanoCLAMP antibody mimetic scaffold as a platform for producing bioprocess-compatible affinity capture ligands

Protein A affinity chromatography is widely used for the large-scale purification of antibodies because of its high yield, selectivity, and compatibility with NaOH sanitation. A general platform to produce robust affinity capture ligands for proteins beyond antibodies would improve bioprocessing eff...

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Detalles Bibliográficos
Autores principales: Suderman, Richard J., Gibson, Shane D., Strecker, Mary, Bonner, Amanda M., Chao, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Methods and Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404686/
https://www.ncbi.nlm.nih.gov/pubmed/37315789
http://dx.doi.org/10.1016/j.jbc.2023.104910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404686/
https://www.ncbi.nlm.nih.gov/pubmed/37315789
http://dx.doi.org/10.1016/j.jbc.2023.104910

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