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Protein engineering of a nanoCLAMP antibody mimetic scaffold as a platform for producing bioprocess-compatible affinity capture ligands
Protein A affinity chromatography is widely used for the large-scale purification of antibodies because of its high yield, selectivity, and compatibility with NaOH sanitation. A general platform to produce robust affinity capture ligands for proteins beyond antibodies would improve bioprocessing eff...
Autores principales: | Suderman, Richard J., Gibson, Shane D., Strecker, Mary, Bonner, Amanda M., Chao, David M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404686/ https://www.ncbi.nlm.nih.gov/pubmed/37315789 http://dx.doi.org/10.1016/j.jbc.2023.104910 |
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