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Dual phenotypic characteristics of P-selectin in a mouse model of hemorrhagic shock and hepatectomy

BACKGROUND: Membrane-bound P-selectin induces endothelial adhesion of leucocytes and amplifies organ inflammations during major trauma, while soluble P-selectin (sP-sel) mediates survival rescue properties. This study characterized the differential effects of P-selectin in a “2-hit” model of hemorrh...

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Detalles Bibliográficos
Autores principales: Chen, Jen-Lung, Cheng, Tzu-Ting, Huang, Chien-Chi, Chang, Hsin-Hou, Lam, Chen-Fuh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404689/
https://www.ncbi.nlm.nih.gov/pubmed/37554775
http://dx.doi.org/10.1016/j.heliyon.2023.e18627