MAP2 caps tau fibrils and inhibits aggregation

Fibrils of the microtubule-associated protein tau are intimately linked to the pathology of Alzheimer’s disease (AD) and related neurodegenerative disorders. A current paradigm for pathology spreading in the human brain is that short tau fibrils transfer between neurons and then recruit naive tau mo...

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Detalles Bibliográficos
Autores principales: Holden, Michael R., Krzesinski, Brad J., Weismiller, Hilary A., Shady, Justin R., Margittai, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404690/
https://www.ncbi.nlm.nih.gov/pubmed/37286038
http://dx.doi.org/10.1016/j.jbc.2023.104891

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404690/
https://www.ncbi.nlm.nih.gov/pubmed/37286038
http://dx.doi.org/10.1016/j.jbc.2023.104891

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