Dopamine-mediated striatal activity and function is enhanced in GlyRα2 knockout animals

The glycine receptor alpha 2 (GlyRα2) is a ligand-gated ion channel which upon activation induces a chloride conductance. Here, we investigated the role of GlyRα2 in dopamine-stimulated striatal cell activity and behavior. We show that depletion of GlyRα2 enhances dopamine-induced increases in the a...

Descripción completa

Detalles Bibliográficos
Autores principales: Devoght, Jens, Comhair, Joris, Morelli, Giovanni, Rigo, Jean-Michel, D'Hooge, Rudi, Touma, Chadi, Palme, Rupert, Dewachter, Ilse, vandeVen, Martin, Harvey, Robert J., Schiffmann, Serge N., Piccart, Elisabeth, Brône, Bert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404725/
https://www.ncbi.nlm.nih.gov/pubmed/37554441
http://dx.doi.org/10.1016/j.isci.2023.107400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404725/
https://www.ncbi.nlm.nih.gov/pubmed/37554441
http://dx.doi.org/10.1016/j.isci.2023.107400

Ejemplares similares