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Dopamine-mediated striatal activity and function is enhanced in GlyRα2 knockout animals

The glycine receptor alpha 2 (GlyRα2) is a ligand-gated ion channel which upon activation induces a chloride conductance. Here, we investigated the role of GlyRα2 in dopamine-stimulated striatal cell activity and behavior. We show that depletion of GlyRα2 enhances dopamine-induced increases in the a...

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Detalles Bibliográficos
Autores principales:	Devoght, Jens, Comhair, Joris, Morelli, Giovanni, Rigo, Jean-Michel, D'Hooge, Rudi, Touma, Chadi, Palme, Rupert, Dewachter, Ilse, vandeVen, Martin, Harvey, Robert J., Schiffmann, Serge N., Piccart, Elisabeth, Brône, Bert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404725/ https://www.ncbi.nlm.nih.gov/pubmed/37554441 http://dx.doi.org/10.1016/j.isci.2023.107400

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