Fluorescent membrane potential assay for drug screening on Kv10.1 channel: identification of BL-1249 as a channel activator

Resting membrane potential is a bioelectric property of all cells. Multiple players govern this property, the ion channels being the most important. Ion channel dysfunction can affect cells’ resting membrane potential and could be associated with numerous diseases. Therefore, the drug discovery focu...

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Detalles Bibliográficos
Autores principales: Gómez-Herrera, Mirsha Aseret, Patlán, Enikar, Estrada-Garrido, Armando, Hernández-Cruz, Arturo, Luis, Enoch
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404814/
https://www.ncbi.nlm.nih.gov/pubmed/37554982
http://dx.doi.org/10.3389/fphar.2023.1238503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404814/
https://www.ncbi.nlm.nih.gov/pubmed/37554982
http://dx.doi.org/10.3389/fphar.2023.1238503

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