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Fluorescent membrane potential assay for drug screening on Kv10.1 channel: identification of BL-1249 as a channel activator
Resting membrane potential is a bioelectric property of all cells. Multiple players govern this property, the ion channels being the most important. Ion channel dysfunction can affect cells’ resting membrane potential and could be associated with numerous diseases. Therefore, the drug discovery focu...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404814/ https://www.ncbi.nlm.nih.gov/pubmed/37554982 http://dx.doi.org/10.3389/fphar.2023.1238503 |