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BET in hematologic tumors: Immunity, pathogenesis, clinical trials and drug combinations
The bromodomain and extra-terminal (BET) proteins act as “readers” for lysine acetylation and facilitate the recruitment of transcriptional elongation complexes. BET protein is associated with transcriptional elongation of genes such as c-MYC and BCL-2, and is involved in the regulation of cell cycl...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chongqing Medical University
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404881/ https://www.ncbi.nlm.nih.gov/pubmed/37554207 http://dx.doi.org/10.1016/j.gendis.2022.03.004 |