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BET in hematologic tumors: Immunity, pathogenesis, clinical trials and drug combinations

The bromodomain and extra-terminal (BET) proteins act as “readers” for lysine acetylation and facilitate the recruitment of transcriptional elongation complexes. BET protein is associated with transcriptional elongation of genes such as c-MYC and BCL-2, and is involved in the regulation of cell cycl...

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Detalles Bibliográficos
Autores principales: Ma, Tao, Chen, Yan, Yi, Zhi-Gang, Li, Yan-Hong, Bai, Jun, Li, Li-Juan, Zhang, Lian-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404881/
https://www.ncbi.nlm.nih.gov/pubmed/37554207
http://dx.doi.org/10.1016/j.gendis.2022.03.004