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The crucial roles of m(6)A RNA modifications in cutaneous cancers: Implications in pathogenesis, metastasis, drug resistance, and targeted therapies

N6-methyladenosine (m(6)A) is the most abundant internal modification on RNA. It is a dynamical and reversible process, which is regulated by m(6)A methyltransferase and m(6)A demethylase. The m(6)A modified RNA can be specifically recognized by the m(6)A reader, leading to RNA splicing, maturation,...

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Detalles Bibliográficos
Autores principales: Huang, Cong, Zhang, Kaoyuan, Guo, Yang, Shen, Changbing, Liu, Xiaoming, Huang, Haiyan, Dou, Xia, Yu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404882/
https://www.ncbi.nlm.nih.gov/pubmed/37554186
http://dx.doi.org/10.1016/j.gendis.2022.03.006