PRMT1 promotes the proliferation and metastasis of gastric cancer cells by recruiting MLXIP for the transcriptional activation of the β-catenin pathway

Protein arginine methyltransferase 1 (PRMT1), a type I PRMT, is overexpressed in gastric cancer (GC) cells. To elucidate the function of PRMT1 in GC, PRMT1 expression in HGC-27 and MKN-45 cells was knocked down by short hairpin RNA (shRNA) or inhibited by PRMT1 inhibitors (AMI-1 or DCLX069), which r...

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Detalles Bibliográficos
Autores principales: Wang, Feng, Chen, Shitong, Peng, Shihan, Zhou, Xujun, Tang, Houyi, Liang, Hanghua, Zhong, Xi, Yang, He, Ke, Xiaoxue, Lü, MuHan, Cui, Hongjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2023
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404965/
https://www.ncbi.nlm.nih.gov/pubmed/37554218
http://dx.doi.org/10.1016/j.gendis.2023.02.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404965/
https://www.ncbi.nlm.nih.gov/pubmed/37554218
http://dx.doi.org/10.1016/j.gendis.2023.02.006

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