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The splicing factor YBX1 promotes the progression of osteosarcoma by upregulating VEGF(165) and downregulating VEGF(165b)

VEGF(165) and its isoform VEGF(165b) have the same length but opposite functions in cancer. Some studies have indicated the important role of VEGF(165) in osteosarcoma (OS); however, VEGF(165b) has not been taken into consideration. This study aims to clarify the roles of the two isoforms in OS and...

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Detalles Bibliográficos
Autores principales: Quan, Bingxuan, Li, Zhigang, Yang, Hongbo, Li, Shuo, Yan, Xiuchun, Wang, Yansong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405001/
https://www.ncbi.nlm.nih.gov/pubmed/37554848
http://dx.doi.org/10.1016/j.heliyon.2023.e18706