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Roquin-1 resolves sepsis-associated acute liver injury by regulating inflammatory profiles via miRNA cargo in extracellular vesicles

Sepsis-associated acute liver injury (SALI) is an independent risk for sepsis-induced death orchestrated by innate and adaptive immune responses. Here, we found that Roquin-1 was decreased during SALI and expressed mainly in monocyte-derived macrophages. Meanwhile, Roquin-1 was correlated with the i...

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Detalles Bibliográficos
Autores principales: Zheng, Lei, Ling, Wei, Zhu, Deming, Li, Zhi, Li, Yousheng, Zhou, Haoming, Kong, Lianbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405074/
https://www.ncbi.nlm.nih.gov/pubmed/37554446
http://dx.doi.org/10.1016/j.isci.2023.107295