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Roquin-1 resolves sepsis-associated acute liver injury by regulating inflammatory profiles via miRNA cargo in extracellular vesicles
Sepsis-associated acute liver injury (SALI) is an independent risk for sepsis-induced death orchestrated by innate and adaptive immune responses. Here, we found that Roquin-1 was decreased during SALI and expressed mainly in monocyte-derived macrophages. Meanwhile, Roquin-1 was correlated with the i...
Autores principales: | Zheng, Lei, Ling, Wei, Zhu, Deming, Li, Zhi, Li, Yousheng, Zhou, Haoming, Kong, Lianbao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405074/ https://www.ncbi.nlm.nih.gov/pubmed/37554446 http://dx.doi.org/10.1016/j.isci.2023.107295 |
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