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Inhibition of NK1.1 signaling attenuates pressure overload-induced heart failure, and consequent pulmonary inflammation and remodeling

BACKGROUND: Inflammation contributes to heart failure (HF) development, the progression from left ventricular failure to pulmonary remodeling, and the consequent right ventricular hypertrophy and failure. NK1.1 plays a critical role in Natural killer (NK) and NK T (NKT) cells, but the role of NK1.1...

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Detalles Bibliográficos
Autores principales: He, Xiaochen, Xu, Rui, Pan, Lihong, Bhattarai, Umesh, Liu, Xiaoguang, Zeng, Heng, Chen, Jian-Xiong, Hall, Michael E., Chen, Yingjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405176/
https://www.ncbi.nlm.nih.gov/pubmed/37554327
http://dx.doi.org/10.3389/fimmu.2023.1215855