Cytokine receptor IL27RA is an NF-κB–responsive gene involved in CD38 upregulation in multiple myeloma

Multiple myeloma (MM) shows constitutive activation of canonical and noncanonical nuclear factor κB (NF-κB) signaling via genetic mutations or tumor microenvironment (TME) stimulations. A subset of MM cell lines showed dependency for cell growth and survival on the canonical NF-κB transcription fact...

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Detalles Bibliográficos
Autores principales: Brownlie, Rebecca J., Kennedy, Ruth, Wilson, Erica B., Milanovic, Maja, Taylor, Claire F., Wang, Dapeng, Davies, John R., Owston, Heather, Adams, Emma J., Stephenson, Sophie, Caeser, Rebecca, Gewurz, Benjamin E., Giannoudis, Peter V., Scuoppo, Claudio, McGonagle, Dennis, Hodson, Daniel J., Tooze, Reuben M., Doody, Gina M., Cook, Gordon, Westhead, David R., Klein, Ulf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Lymphoid Neoplasia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405202/
https://www.ncbi.nlm.nih.gov/pubmed/36867577
http://dx.doi.org/10.1182/bloodadvances.2022009044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405202/
https://www.ncbi.nlm.nih.gov/pubmed/36867577
http://dx.doi.org/10.1182/bloodadvances.2022009044

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