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Two different isoforms of osteopontin modulate myelination and axonal integrity

Abnormal myelination underlies the pathology of white matter diseases such as preterm white matter injury and multiple sclerosis. Osteopontin (OPN) has been suggested to play a role in myelination. Murine OPN mRNA is translated into a secreted isoform (sOPN) or an intracellular isoform (iOPN). Wheth...

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Detalles Bibliográficos
Autores principales: Nilsson, Gisela, Mottahedin, Amin, Zelco, Aura, Lauschke, Volker M., Ek, C. Joakim, Song, Juan, Ardalan, Maryam, Hua, Sha, Zhang, Xiaoli, Mallard, Carina, Hagberg, Henrik, Leavenworth, Jianmei W., Wang, Xiaoyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405251/
https://www.ncbi.nlm.nih.gov/pubmed/37554545
http://dx.doi.org/10.1096/fba.2023-00030