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Valosin containing protein (VCP): initiator, modifier, and potential drug target for neurodegenerative diseases
The AAA(+) ATPase valosin containing protein (VCP) is essential for cell and organ homeostasis, especially in cells of the nervous system. As part of a large network, VCP collaborates with many cofactors to ensure proteostasis under normal, stress, and disease conditions. A large number of mutations...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405438/ https://www.ncbi.nlm.nih.gov/pubmed/37545006 http://dx.doi.org/10.1186/s13024-023-00639-y |