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Valosin containing protein (VCP): initiator, modifier, and potential drug target for neurodegenerative diseases

The AAA(+) ATPase valosin containing protein (VCP) is essential for cell and organ homeostasis, especially in cells of the nervous system. As part of a large network, VCP collaborates with many cofactors to ensure proteostasis under normal, stress, and disease conditions. A large number of mutations...

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Detalles Bibliográficos
Autores principales: Chu, Siwei, Xie, Xinyi, Payan, Carla, Stochaj, Ursula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405438/
https://www.ncbi.nlm.nih.gov/pubmed/37545006
http://dx.doi.org/10.1186/s13024-023-00639-y