Application of fused-grid-based CYP-Template systems for genotoxic substances to understand the metabolisms

Understanding of metabolic processes is a key factor to evaluate biological effects of carcinogen and mutagens. Applicability of fused-grid Template* systems of CYP enzymes (Drug Metab Pharmacokinet 2019, 2020, 2021, and 2022) was tested for three phenomena. (1) Possible causal relationships between...

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Detalles Bibliográficos
Autores principales: Yamazoe, Yasushi, Murayama, Norie, Kawamura, Tomoko, Yamada, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405451/
https://www.ncbi.nlm.nih.gov/pubmed/37544994
http://dx.doi.org/10.1186/s41021-023-00275-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405451/
https://www.ncbi.nlm.nih.gov/pubmed/37544994
http://dx.doi.org/10.1186/s41021-023-00275-4

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