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Application of fused-grid-based CYP-Template systems for genotoxic substances to understand the metabolisms
Understanding of metabolic processes is a key factor to evaluate biological effects of carcinogen and mutagens. Applicability of fused-grid Template* systems of CYP enzymes (Drug Metab Pharmacokinet 2019, 2020, 2021, and 2022) was tested for three phenomena. (1) Possible causal relationships between...
Autores principales: | Yamazoe, Yasushi, Murayama, Norie, Kawamura, Tomoko, Yamada, Takashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405451/ https://www.ncbi.nlm.nih.gov/pubmed/37544994 http://dx.doi.org/10.1186/s41021-023-00275-4 |
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