Hypoxic oligodendrocyte precursor cell-derived VEGFA is associated with blood–brain barrier impairment

Cerebral small vessel disease is characterised by decreased cerebral blood flow and blood–brain barrier impairments which play a key role in the development of white matter lesions. We hypothesised that cerebral hypoperfusion causes local hypoxia, affecting oligodendrocyte precursor cell—endothelial...

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Detalles Bibliográficos
Autores principales: Manukjan, Narek, Majcher, Daria, Leenders, Peter, Caiment, Florian, van Herwijnen, Marcel, Smeets, Hubert J., Suidgeest, Ernst, van der Weerd, Louise, Vanmierlo, Tim, Jansen, Jacobus F. A., Backes, Walter H., van Oostenbrugge, Robert J., Staals, Julie, Fulton, Daniel, Ahmed, Zubair, Blankesteijn, W. Matthijs, Foulquier, Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405482/
https://www.ncbi.nlm.nih.gov/pubmed/37550790
http://dx.doi.org/10.1186/s40478-023-01627-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405482/
https://www.ncbi.nlm.nih.gov/pubmed/37550790
http://dx.doi.org/10.1186/s40478-023-01627-5

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