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Preclinical evaluation of Mito-LND, a targeting mitochondrial metabolism inhibitor, for glioblastoma treatment

BACKGROUND: Glioblastoma (GBM) is a brain tumor with the highest level of malignancy and the worst prognosis in the central nervous system. Mitochondrial metabolism plays a vital role in the occurrence and development of cancer, which provides critical substances to support tumor anabolism. Mito-LND...

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Detalles Bibliográficos
Autores principales: Guo, Tongxuan, Wu, Changyong, Zhou, Lingni, Zhang, Junhao, Wang, Wanzhou, Shen, Yang, Zhang, Ludong, Niu, Mingshan, Zhang, Xu, Yu, Rutong, Liu, Xuejiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405494/
https://www.ncbi.nlm.nih.gov/pubmed/37550679
http://dx.doi.org/10.1186/s12967-023-04332-y