HIF-1α increases the osteogenic capacity of ADSCs by coupling angiogenesis and osteogenesis via the HIF-1α/VEGF/AKT/mTOR signaling pathway

BACKGROUND: Stabilization and increased activity of hypoxia-inducible factor 1-α (HIF-1α) can directly increase cancellous bone formation and play an essential role in bone modeling and remodeling. However, whether an increased HIF-1α expression in adipose-derived stem cells (ADSCs) increases osteog...

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Detalles Bibliográficos
Autores principales: Song, Shuang, Zhang, Guanhua, Chen, Xutao, Zheng, Jian, Liu, Xiangdong, Wang, Yiqing, Chen, Zijun, Wang, Yuxi, Song, Yingliang, Zhou, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405507/
https://www.ncbi.nlm.nih.gov/pubmed/37550736
http://dx.doi.org/10.1186/s12951-023-02020-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405507/
https://www.ncbi.nlm.nih.gov/pubmed/37550736
http://dx.doi.org/10.1186/s12951-023-02020-z

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