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Human serum albumin as a copper source for anticancer thiosemicarbazones

Thiosemicarbazones (TSCs) are a class of biologically active compounds with promising anticancer activity. Their typical mechanism, especially of the clinically far developed representative Triapine, is chelation of iron (Fe), with the Fe-containing enzyme ribonucleotide reductase as primary intrace...

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Detalles Bibliográficos
Autores principales: Schaier, Martin, Falcone, Enrico, Prstek, Tomas, Vileno, Bertrand, Hager, Sonja, Keppler, Bernhard K, Heffeter, Petra, Koellensperger, Gunda, Faller, Peter, Kowol, Christian R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405564/
https://www.ncbi.nlm.nih.gov/pubmed/37505477
http://dx.doi.org/10.1093/mtomcs/mfad046