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Human serum albumin as a copper source for anticancer thiosemicarbazones
Thiosemicarbazones (TSCs) are a class of biologically active compounds with promising anticancer activity. Their typical mechanism, especially of the clinically far developed representative Triapine, is chelation of iron (Fe), with the Fe-containing enzyme ribonucleotide reductase as primary intrace...
Autores principales: | Schaier, Martin, Falcone, Enrico, Prstek, Tomas, Vileno, Bertrand, Hager, Sonja, Keppler, Bernhard K, Heffeter, Petra, Koellensperger, Gunda, Faller, Peter, Kowol, Christian R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405564/ https://www.ncbi.nlm.nih.gov/pubmed/37505477 http://dx.doi.org/10.1093/mtomcs/mfad046 |
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