A Nrf2-OSGIN1&2-HSP70 axis mediates cigarette smoke-induced endothelial detachment: implications for plaque erosion

AIMS: Endothelial erosion of plaques is responsible for ∼30% of acute coronary syndromes (ACS). Smoking is a risk factor for plaque erosion, which most frequently occurs on the upstream surface of plaques where the endothelium experiences elevated shear stress. We sought to recreate these conditions...

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Detalles Bibliográficos
Autores principales: Satta, Sandro, Beal, Robert, Smith, Rhys, Luo, Xing, Ferris, Glenn R, Langford-Smith, Alex, Teasdale, Jack, Ajime, Tom Tanjeko, Serré, Jef, Hazell, Georgina, Newby, Graciela Sala, Johnson, Jason L, Kurinna, Svitlana, Humphries, Martin J, Gayan-Ramirez, Ghislaine, Libby, Peter, Degens, Hans, Yu, Bo, Johnson, Thomas, Alexander, Yvonne, Jia, Haibo, Newby, Andrew C, White, Stephen J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405570/
https://www.ncbi.nlm.nih.gov/pubmed/36804807
http://dx.doi.org/10.1093/cvr/cvad022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405570/
https://www.ncbi.nlm.nih.gov/pubmed/36804807
http://dx.doi.org/10.1093/cvr/cvad022

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