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“… wise, amazed, temp’rate, and furious, Loyal and neutral, in a moment”: first heritability analysis of affective temperaments reports remarkably high SNP-based heritability

INTRODUCTION: Depression shows a moderate heritability of 37-42%, which can be up to 75% in severely depressed samples 75%. At the same time SNP-based heritability of depression in GWAS-s is around 8-9%. Heterogeneity of the depressive phenotype may contribute not only to the lack of understanding i...

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Detalles Bibliográficos
Autores principales: Gonda, X., Torok, D., Eszlari, N., Gyorik, D., Millinghoffer, A., Bagdy, G., Juhasz, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405677/
http://dx.doi.org/10.1192/j.eurpsy.2023.768