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The yes-associated protein (YAP) is associated with resistance to anti-GD2 immunotherapy in neuroblastoma through downregulation of ST8SIA1

Pediatric patients with high-risk neuroblastoma often relapse with chemotherapy-resistant, incurable disease. Relapsed neuroblastomas harbor chemo-resistant mesenchymal tumor cells and increased expression/activity of the transcriptional co-regulator, the Yes-Associated Protein (YAP). Patients with...

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Detalles Bibliográficos
Autores principales: Pilgrim, Adeiye A., Jonus, Hunter C., Ho, Andrew, Cole, Anna C., Shim, Jenny, Goldsmith, Kelly C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405770/
https://www.ncbi.nlm.nih.gov/pubmed/37554309
http://dx.doi.org/10.1080/2162402X.2023.2240678