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Vitamin D receptor-deficient keratinocytes-derived exosomal miR-4505 promotes the macrophage polarization towards the M1 phenotype

BACKGROUND: The vitamin D receptor (VDR) has a low level of expression in the keratinocytes of patients with psoriasis and plays a role in the development of the disease. Furthermore, the crosstalk between macrophages and psoriatic keratinocytes-derived exosomes is critical for psoriasis progression...

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Detalles Bibliográficos
Autores principales: Sun, Wen, Chen, Jianqin, Li, Jingting, She, Xiaoguang, Ma, Hu, Wang, Shali, Liu, Jing, Yuan, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405794/
https://www.ncbi.nlm.nih.gov/pubmed/37554338
http://dx.doi.org/10.7717/peerj.15798