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The SIRT1-c-Myc axis in regulation of stem cells
SIRT1 is the most conserved mammalian NAD(+)-dependent protein deacetylase. Through deacetylation of transcriptional factors and co-factors, this protein modification enzyme is critically involved in metabolic and epigenetic regulation of stem cells, which is functionally important in maintaining th...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405831/ https://www.ncbi.nlm.nih.gov/pubmed/37554307 http://dx.doi.org/10.3389/fcell.2023.1236968 |