BCR-ABL1-driven exosome-miR130b-3p-mediated gap-junction Cx43 MSC intercellular communications imply therapies of leukemic subclonal evolution

Rationale: In the bone marrow microenvironment (BMME), mesenchymal stem/stromal cells (MSCs) control the self-renewal of both healthy and cancerous hematopoietic stem/progenitor cells (HSPCs). We previously showed that in vivo leukemia-derived MSCs change neighbor MSCs into leukemia-permissive state...

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Detalles Bibliográficos
Autores principales: Chai, Chengyan, Sui, Ke, Tang, Jun, Yu, Hao, Yang, Chao, Zhang, Hongyang, Li, Shengwen Calvin, Zhong, Jiang F., Wang, Zheng, Zhang, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405834/
https://www.ncbi.nlm.nih.gov/pubmed/37554265
http://dx.doi.org/10.7150/thno.83178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405834/
https://www.ncbi.nlm.nih.gov/pubmed/37554265
http://dx.doi.org/10.7150/thno.83178

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