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BCR-ABL1-driven exosome-miR130b-3p-mediated gap-junction Cx43 MSC intercellular communications imply therapies of leukemic subclonal evolution
Rationale: In the bone marrow microenvironment (BMME), mesenchymal stem/stromal cells (MSCs) control the self-renewal of both healthy and cancerous hematopoietic stem/progenitor cells (HSPCs). We previously showed that in vivo leukemia-derived MSCs change neighbor MSCs into leukemia-permissive state...
Autores principales: | Chai, Chengyan, Sui, Ke, Tang, Jun, Yu, Hao, Yang, Chao, Zhang, Hongyang, Li, Shengwen Calvin, Zhong, Jiang F., Wang, Zheng, Zhang, Xi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405834/ https://www.ncbi.nlm.nih.gov/pubmed/37554265 http://dx.doi.org/10.7150/thno.83178 |
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