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A Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Novel Intravenous Formulation of Meloxicam (QP001) in Healthy Chinese Subjects

BACKGROUND: Meloxicam is a selective cyclooxygenase-2 inhibitor used for pain relief, but its poor solubility limits its clinical applications. QP001 is a novel intravenous formulation of meloxicam developed with PEG and pH regulator to improve its solubility. This study aimed to evaluate the safety...

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Detalles Bibliográficos
Autores principales: Ma, Junlong, Huang, Jie, Zou, Chan, Wu, Qian, Xie, Jinlian, Zhang, Xingfei, Yang, Xiaoyan, Yang, Shuang, Wu, Ziteng, Jiang, Yan, Yu, Sen, Zhang, Xuqing, Yang, Guoping, Li, Mingyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406176/
https://www.ncbi.nlm.nih.gov/pubmed/37554228
http://dx.doi.org/10.2147/DDDT.S418730