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Investigation of Human Intrathecal Solute Transport Dynamics Using a Novel in vitro Cerebrospinal Fluid System Analog

BACKGROUND: Understanding the relationship between cerebrospinal fluid (CSF) dynamics and intrathecal drug delivery (ITDD) injection parameters is essential to improve treatment of central nervous system (CNS) disorders. METHODS: An anatomically detailed in vitro model of the complete CSF system was...

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Detalles Bibliográficos
Autores principales: Seiner, Akari, Burla, Goutham Kumar Reddy, Shrestha, Dev, Bowen, Mayumi, Horvath, Joshua D., Martin, Bryn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406265/
https://www.ncbi.nlm.nih.gov/pubmed/37555174
http://dx.doi.org/10.3389/fnimg.2022.879098