Isotope tracing reveals bacterial catabolism of host-derived glutathione during Helicobacter pylori infection

Mammalian cells synthesize the antioxidant glutathione (GSH) to shield cellular biomolecules from oxidative damage. Certain bacteria, including the gastric pathogen Helicobacter pylori, can perturb host GSH homeostasis. H. pylori infection significantly decreases GSH levels in host tissues, which ha...

Descripción completa

Detalles Bibliográficos
Autores principales: Baskerville, Maia J., Kovalyova, Yekaterina, Mejías-Luque, Raquel, Gerhard, Markus, Hatzios, Stavroula K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406306/
https://www.ncbi.nlm.nih.gov/pubmed/37494402
http://dx.doi.org/10.1371/journal.ppat.1011526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406306/
https://www.ncbi.nlm.nih.gov/pubmed/37494402
http://dx.doi.org/10.1371/journal.ppat.1011526

Ejemplares similares