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Suppression of viral RNA polymerase activity is necessary for persistent infection during the transformation of measles virus into SSPE virus

Subacute sclerosing panencephalitis (SSPE) is a fatal neurodegenerative disease caused by measles virus (MV), which typically develops 7 to 10 years after acute measles. During the incubation period, MV establishes a persistent infection in the brain and accumulates mutations that generate neuropath...

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Detalles Bibliográficos
Autores principales: Sakamoto, Kento, Konami, Miho, Kameda, Shinra, Satoh, Yuto, Wakimoto, Hiroshi, Kitagawa, Yoshinori, Gotoh, Bin, Jiang, Da-Peng, Hotta, Hak, Itoh, Masae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406308/
https://www.ncbi.nlm.nih.gov/pubmed/37494386
http://dx.doi.org/10.1371/journal.ppat.1011528