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Self-assembled GLP-1/glucagon peptide nanofibrils prolong inhibition of food intake

INTRODUCTION: Oxyntomodulin (Oxm) hormone peptide has a number of beneficial effects on nutrition and metabolism including increased energy expenditure and reduced body weight gain. Despite its many advantages as a potential therapeutic agent, Oxm is subjected to rapid renal clearance and protease d...

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Detalles Bibliográficos
Autores principales: Ouberai, Myriam M., Gomes Dos Santos, Ana L., Kinna, Sonja, Hornigold, David C., Baker, David, Naylor, Jacqueline, Liang, Lihuan, Corkill, Dominic J., Welland, Mark E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406450/
https://www.ncbi.nlm.nih.gov/pubmed/37554763
http://dx.doi.org/10.3389/fendo.2023.1217021